Cook the macaroni according to package directions, then drain and set aside.
In a separate pan, melt the butter over medium heat.
Gradually add the water, garlic powder, onion powder, dried parsley, salt, and black pepper, whisking constantly until the mixture thickens.
Reduce the heat to low and add the shredded cheddar cheese, stirring until the cheese has melted and the sauce is smooth.
Add the cooked macaroni to the cheese sauce and stir until everything is well combined.
Serve immediately and enjoy your delicious Mac and Cheese without Milk!